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Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

BACKGROUND: Eukaryotic tRNA splicing is an essential process in the transformation of a primary tRNA transcript into a mature functional tRNA molecule. 5′-phosphate ligation involves two steps: a healing reaction catalyzed by polynucleotide kinase (PNK) in association with cyclic phosphodiesterase (...

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Detalles Bibliográficos
Autores principales:	Muruganandam, Gopinath, Raasakka, Arne, Myllykoski, Matti, Kursula, Inari, Kursula, Petri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434554/ https://www.ncbi.nlm.nih.gov/pubmed/28511668 http://dx.doi.org/10.1186/s12858-017-0084-2

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