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Tryptophan catabolism and immune activation in primary and chronic HIV infection

BACKGROUND: Kynurenine/Tryptophan ratio (KTR) is increased in HIV infection, and linked to immune activation. We hypothesized that early cART initiation results in lower KTR compared to late initiation. Furthermore, we hypothesized that KTR prior to cART is a predictor of the magnitude of subsequent...

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Detalles Bibliográficos
Autores principales:	Gelpi, Marco, Hartling, Hans J., Ueland, Per M., Ullum, Henrik, Trøseid, Marius, Nielsen, Susanne D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434617/ https://www.ncbi.nlm.nih.gov/pubmed/28511640 http://dx.doi.org/10.1186/s12879-017-2456-z

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