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Rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy

BACKGROUND: There is growing evidence from the literature that right anterior minithoracotomy aortic valve replacement (RAT-AVR) improves clinical outcome. However, increased cross clamp time is the strongest argument for surgeons not performing RAT-AVR. Rapid deployment aortic valve systems have th...

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Autores principales: Bening, Constanze, Hamouda, Khaled, Oezkur, Mehmet, Schimmer, Christoph, Schade, Ina, Gorski, Armin, Aleksic, Ivan, Leyh, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434633/
https://www.ncbi.nlm.nih.gov/pubmed/28511707
http://dx.doi.org/10.1186/s13019-017-0598-0
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author Bening, Constanze
Hamouda, Khaled
Oezkur, Mehmet
Schimmer, Christoph
Schade, Ina
Gorski, Armin
Aleksic, Ivan
Leyh, Rainer
author_facet Bening, Constanze
Hamouda, Khaled
Oezkur, Mehmet
Schimmer, Christoph
Schade, Ina
Gorski, Armin
Aleksic, Ivan
Leyh, Rainer
author_sort Bening, Constanze
collection PubMed
description BACKGROUND: There is growing evidence from the literature that right anterior minithoracotomy aortic valve replacement (RAT-AVR) improves clinical outcome. However, increased cross clamp time is the strongest argument for surgeons not performing RAT-AVR. Rapid deployment aortic valve systems have the potential to decrease cross-clamp time and ease this procedure. We assessed clinical outcome of rapid deployment and conventional valves through RAT. METHODS: Sixty-eight patients (mean age 76 ± 6 years, 32% females) underwent RAT-AVR between 9/2013 and 7/2015. According to the valve type implanted the patients were divided into two groups. In 43 patients (R-group; mean age 74.1 ± 6.6 years) a rapid deployment valve system (Edwards Intuity, Edwards Lifesciences Corp; Irvine, Calif) and in 25 patients (C-group; mean age 74.2 ± 6.6 years) a conventional stented biological aortic valve was implanted. RESULTS: Aortic cross-clamp (42.1 ± 12 min vs. 68.3 ± 20.3 min; p < 0.001) and bypass time (80.4 ± 39.3 min vs. 106.6 ± 23.2 min; p = 0.001) were shorter in the rapid deployment group (R-group). We observed no differences in clinical outcome. Postoperative gradients (R-group: max gradient, 14.3 ± 8 mmHg vs. 15.5 ± 5 mmHg (C-group), mean gradient, 9.2 ± 1.7 mmHg (R-group) vs. 9.1 ± 2.3 mmHg (C-group) revealed no differences. However, larger prostheses were implanted in C-group (25 mm; IQR 23–27 mm vs. 23 mm; IQR 21–25; p = 0.009). CONCLUSIONS: Our data suggest that the rapid deployment aortic valve system reduced cross clamp and bypass time in patients undergoing RAT-AVR with similar hemodynamics as with larger size stented prosthesis. However, larger studies and long-term follow-up are mandatory to confirm our findings.
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spelling pubmed-54346332017-05-18 Rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy Bening, Constanze Hamouda, Khaled Oezkur, Mehmet Schimmer, Christoph Schade, Ina Gorski, Armin Aleksic, Ivan Leyh, Rainer J Cardiothorac Surg Research Article BACKGROUND: There is growing evidence from the literature that right anterior minithoracotomy aortic valve replacement (RAT-AVR) improves clinical outcome. However, increased cross clamp time is the strongest argument for surgeons not performing RAT-AVR. Rapid deployment aortic valve systems have the potential to decrease cross-clamp time and ease this procedure. We assessed clinical outcome of rapid deployment and conventional valves through RAT. METHODS: Sixty-eight patients (mean age 76 ± 6 years, 32% females) underwent RAT-AVR between 9/2013 and 7/2015. According to the valve type implanted the patients were divided into two groups. In 43 patients (R-group; mean age 74.1 ± 6.6 years) a rapid deployment valve system (Edwards Intuity, Edwards Lifesciences Corp; Irvine, Calif) and in 25 patients (C-group; mean age 74.2 ± 6.6 years) a conventional stented biological aortic valve was implanted. RESULTS: Aortic cross-clamp (42.1 ± 12 min vs. 68.3 ± 20.3 min; p < 0.001) and bypass time (80.4 ± 39.3 min vs. 106.6 ± 23.2 min; p = 0.001) were shorter in the rapid deployment group (R-group). We observed no differences in clinical outcome. Postoperative gradients (R-group: max gradient, 14.3 ± 8 mmHg vs. 15.5 ± 5 mmHg (C-group), mean gradient, 9.2 ± 1.7 mmHg (R-group) vs. 9.1 ± 2.3 mmHg (C-group) revealed no differences. However, larger prostheses were implanted in C-group (25 mm; IQR 23–27 mm vs. 23 mm; IQR 21–25; p = 0.009). CONCLUSIONS: Our data suggest that the rapid deployment aortic valve system reduced cross clamp and bypass time in patients undergoing RAT-AVR with similar hemodynamics as with larger size stented prosthesis. However, larger studies and long-term follow-up are mandatory to confirm our findings. BioMed Central 2017-05-16 /pmc/articles/PMC5434633/ /pubmed/28511707 http://dx.doi.org/10.1186/s13019-017-0598-0 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Bening, Constanze
Hamouda, Khaled
Oezkur, Mehmet
Schimmer, Christoph
Schade, Ina
Gorski, Armin
Aleksic, Ivan
Leyh, Rainer
Rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy
title Rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy
title_full Rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy
title_fullStr Rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy
title_full_unstemmed Rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy
title_short Rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy
title_sort rapid deployment valve system shortens operative times for aortic valve replacement through right anterior minithoracotomy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434633/
https://www.ncbi.nlm.nih.gov/pubmed/28511707
http://dx.doi.org/10.1186/s13019-017-0598-0
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