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Good vs complementary genes for parasite resistance and the evolution of mate choice

BACKGROUND: Female mate choice may be adaptive when males exhibit heritable genetic variation at loci encoding resistance to infectious disease. The Hamilton-Zuk hypothesis predicts that females should assess the genetic quality of males by monitoring traits that indicate health and vigor (condition...

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Autores principales: Howard, R Stephen, Lively, Curtis M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC543473/
https://www.ncbi.nlm.nih.gov/pubmed/15555062
http://dx.doi.org/10.1186/1471-2148-4-48
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author Howard, R Stephen
Lively, Curtis M
author_facet Howard, R Stephen
Lively, Curtis M
author_sort Howard, R Stephen
collection PubMed
description BACKGROUND: Female mate choice may be adaptive when males exhibit heritable genetic variation at loci encoding resistance to infectious disease. The Hamilton-Zuk hypothesis predicts that females should assess the genetic quality of males by monitoring traits that indicate health and vigor (condition-dependent choice, or CD). Alternatively, some females may employ a more direct method of screening and select mates based on the dissimilarity of alleles at the major histocompatibility loci (we refer to this as opposites-attract, or OA). Empirical studies suggest that both forms of mate choice exist, but little is known about the potential for natural selection to shape the two strategies in nature. RESULTS: We used computer simulation models to examine the evolutionary fates of the two forms of mate choice in populations at risk for infection by debilitating parasites. We found that populations exhibiting random mating (no mate choice) can be invaded and replaced completely by individuals practicing CD type mate choice. We also found that an allele encoding OA choice can increase when rare in randomly mating populations, but that it does not go to fixation under selection. A similar result was obtained when the OA strategy was introduced into populations practicing CD mate choice. As before, we found that the OA choice allele will increase when rare, and that it will not go to fixation under selection. The converse however was not true, as CD individuals gain no rare advantage when introduced into an OA population. CONCLUSIONS: Taken together, the results suggest that, when rare, OA is the best strategy for parasite evasion (of those considered here). The consequence of OA increasing in the population, however, is to reduce the parasite driven genotype oscillations and facilitate the breakdown of linkage disequilibrium at the disease-resistance loci. This leads to a neutrally stable situation in which different strategies have equal fitness, and suggests that multiple forms of mate choice may be expected to occur in populations at risk from infectious disease.
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spelling pubmed-5434732005-01-08 Good vs complementary genes for parasite resistance and the evolution of mate choice Howard, R Stephen Lively, Curtis M BMC Evol Biol Research Article BACKGROUND: Female mate choice may be adaptive when males exhibit heritable genetic variation at loci encoding resistance to infectious disease. The Hamilton-Zuk hypothesis predicts that females should assess the genetic quality of males by monitoring traits that indicate health and vigor (condition-dependent choice, or CD). Alternatively, some females may employ a more direct method of screening and select mates based on the dissimilarity of alleles at the major histocompatibility loci (we refer to this as opposites-attract, or OA). Empirical studies suggest that both forms of mate choice exist, but little is known about the potential for natural selection to shape the two strategies in nature. RESULTS: We used computer simulation models to examine the evolutionary fates of the two forms of mate choice in populations at risk for infection by debilitating parasites. We found that populations exhibiting random mating (no mate choice) can be invaded and replaced completely by individuals practicing CD type mate choice. We also found that an allele encoding OA choice can increase when rare in randomly mating populations, but that it does not go to fixation under selection. A similar result was obtained when the OA strategy was introduced into populations practicing CD mate choice. As before, we found that the OA choice allele will increase when rare, and that it will not go to fixation under selection. The converse however was not true, as CD individuals gain no rare advantage when introduced into an OA population. CONCLUSIONS: Taken together, the results suggest that, when rare, OA is the best strategy for parasite evasion (of those considered here). The consequence of OA increasing in the population, however, is to reduce the parasite driven genotype oscillations and facilitate the breakdown of linkage disequilibrium at the disease-resistance loci. This leads to a neutrally stable situation in which different strategies have equal fitness, and suggests that multiple forms of mate choice may be expected to occur in populations at risk from infectious disease. BioMed Central 2004-11-19 /pmc/articles/PMC543473/ /pubmed/15555062 http://dx.doi.org/10.1186/1471-2148-4-48 Text en Copyright © 2004 Howard and Lively; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Howard, R Stephen
Lively, Curtis M
Good vs complementary genes for parasite resistance and the evolution of mate choice
title Good vs complementary genes for parasite resistance and the evolution of mate choice
title_full Good vs complementary genes for parasite resistance and the evolution of mate choice
title_fullStr Good vs complementary genes for parasite resistance and the evolution of mate choice
title_full_unstemmed Good vs complementary genes for parasite resistance and the evolution of mate choice
title_short Good vs complementary genes for parasite resistance and the evolution of mate choice
title_sort good vs complementary genes for parasite resistance and the evolution of mate choice
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC543473/
https://www.ncbi.nlm.nih.gov/pubmed/15555062
http://dx.doi.org/10.1186/1471-2148-4-48
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