Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis

OBJECTIVE: To identify risk alleles relevant to the causal and biologic mechanisms of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). METHODS: A genome‐wide association study and subsequent replication study were conducted in a total cohort of 1,986 cases of AAV (patients wit...

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Detalles Bibliográficos
Autores principales: Merkel, Peter A., Xie, Gang, Monach, Paul A., Ji, Xuemei, Ciavatta, Dominic J., Byun, Jinyoung, Pinder, Benjamin D., Zhao, Ai, Zhang, Jinyi, Tadesse, Yohannes, Qian, David, Weirauch, Matthew, Nair, Rajan, Tsoi, Alex, Pagnoux, Christian, Carette, Simon, Chung, Sharon, Cuthbertson, David, Davis, John C., Dellaripa, Paul F., Forbess, Lindsy, Gewurz‐Singer, Ora, Hoffman, Gary S., Khalidi, Nader, Koening, Curry, Langford, Carol A., Mahr, Alfred D., McAlear, Carol, Moreland, Larry, Seo, E. Philip, Specks, Ulrich, Spiera, Robert F., Sreih, Antoine, St.Clair, E. William, Stone, John H., Ytterberg, Steven R., Elder, James T., Qu, Jia, Ochi, Toshiki, Hirano, Naoto, Edberg, Jeffrey C., Falk, Ronald J., Amos, Christopher I., Siminovitch, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Vasculitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434905/
https://www.ncbi.nlm.nih.gov/pubmed/28029757
http://dx.doi.org/10.1002/art.40034

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