Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus

OBJECTIVE: Interferon‐γ (IFNγ) is implicated in the pathogenesis of discoid lupus erythematosus (DLE). This study sought to evaluate a single dose of AMG 811, an anti‐IFNγ antibody, in patients with DLE. METHODS: The study was designed as a phase I randomized, double‐blind, placebo‐controlled crosso...

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Detalles Bibliográficos
Autores principales: Werth, Victoria P., Fiorentino, David, Sullivan, Barbara A., Boedigheimer, Michael J., Chiu, Kit, Wang, Christine, Arnold, Gregory E., Damore, Michael A., Bigler, Jeannette, Welcher, Andrew A., Russell, Chris B., Martin, David A., Chung, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Systemic Lupus Erythematosus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434930/
https://www.ncbi.nlm.nih.gov/pubmed/28118537
http://dx.doi.org/10.1002/art.40052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434930/
https://www.ncbi.nlm.nih.gov/pubmed/28118537
http://dx.doi.org/10.1002/art.40052

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