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Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis

The developmental morphogen Sonic hedgehog (Shh) may continue to play a sustaining role in adult motor neurons, of potential relevance to motor neuron diseases including amyotrophic lateral sclerosis. The Shh signaling pathway is incompletely understood and interactions with other signaling pathways...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoxing, Drannik, Anna, Jiang, Fan, Peterson, Randy, Turnbull, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434959/
https://www.ncbi.nlm.nih.gov/pubmed/27984541
http://dx.doi.org/10.1097/WNR.0000000000000725

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