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Expression of Recombinant Phosphodiesterases 3A and 3B Using Baculovirus Expression System

BACKGROUND: Phosphodiesterase 3A (PDE3A) and phosphodiesterase 3B (PDE3B) play a critical role in the regulation of intracellular level of adenosine 3´,5´-cyclic monophosphate (cyclic AMP, cAMP) and guanosine 3´,5´-cyclic monophosphate (cyclic GMP, cGMP). Subsequently PDE3 inhibitors have shown to r...

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Detalles Bibliográficos
Autores principales: Yan, Yongmin, Jiang, Wenqian, Liu, Jingwen, Xu, Wenrong, Qian, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434993/
https://www.ncbi.nlm.nih.gov/pubmed/28959341
http://dx.doi.org/10.15171/ijb.1400