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Pharmacokinetics and Acid Suppressant Efficacy of Esomeprazole after Intravenous, Oral, and Subcutaneous Administration to Healthy Beagle Dogs

BACKGROUND: Esomeprazole is an S‐enantiomer of omeprazole that has favorable pharmacokinetics and efficacious acid suppressant properties in humans. However, the pharmacokinetics and effects on intragastric pH of esomeprazole in dogs have not been reported. OBJECTIVE: To determine the pharmacokineti...

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Detalles Bibliográficos
Autores principales: Hwang, J.‐H., Jeong, J.‐W., Song, G.‐H., Koo, T.‐S., Seo, K.‐W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435062/
https://www.ncbi.nlm.nih.gov/pubmed/28407418
http://dx.doi.org/10.1111/jvim.14713

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