Inference of Epistatic Effects Leading to Entrenchment and Drug Resistance in HIV-1 Protease

Understanding the complex mutation patterns that give rise to drug resistant viral strains provides a foundation for developing more effective treatment strategies for HIV/AIDS. Multiple sequence alignments of drug-experienced HIV-1 protease sequences contain networks of many pair correlations which...

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Detalles Bibliográficos
Autores principales: Flynn, William F., Haldane, Allan, Torbett, Bruce E., Levy, Ronald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Fast Track
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435099/
https://www.ncbi.nlm.nih.gov/pubmed/28369521
http://dx.doi.org/10.1093/molbev/msx095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435099/
https://www.ncbi.nlm.nih.gov/pubmed/28369521
http://dx.doi.org/10.1093/molbev/msx095

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