Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease

OBJECTIVES: To assess the neurobiological substrate of initial cognitive decline in Parkinson’s disease (PD) to inform patient management, clinical trial design, and development of treatments. METHODS: We longitudinally assessed, up to 3 years, 423 newly diagnosed patients with idiopathic PD, untrea...

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Detalles Bibliográficos
Autores principales: Caspell-Garcia, Chelsea, Simuni, Tanya, Tosun-Turgut, Duygu, Wu, I-Wei, Zhang, Yu, Nalls, Mike, Singleton, Andrew, Shaw, Leslie A., Kang, Ju-Hee, Trojanowski, John Q., Siderowf, Andrew, Coffey, Christopher, Lasch, Shirley, Aarsland, Dag, Burn, David, Chahine, Lana M., Espay, Alberto J., Foster, Eric D., Hawkins, Keith A., Litvan, Irene, Richard, Irene, Weintraub, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435130/
https://www.ncbi.nlm.nih.gov/pubmed/28520803
http://dx.doi.org/10.1371/journal.pone.0175674

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