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Differences in SpeB protease activity among group A streptococci associated with superficial, invasive, and autoimmune disease

The secreted cysteine proteinase SpeB is an important virulence factor of group A streptococci (GAS), whereby SpeB activity varies widely among strains. To establish the degree to which SpeB activity correlates with disease, GAS organisms were recovered from patients with pharyngitis, impetigo, inva...

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Detalles Bibliográficos
Autores principales: Ly, Anhphan T., Noto, John P., Walwyn, Odaelys L., Tanz, Robert R., Shulman, Stanford T., Kabat, William, Bessen, Debra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435240/
https://www.ncbi.nlm.nih.gov/pubmed/28545045
http://dx.doi.org/10.1371/journal.pone.0177784