The role of miR-451 in the switching between proliferation and migration in malignant glioma cells: AMPK signaling, mTOR modulation and Rac1 activation required

Glioblastoma multiforme (GBM), WHO grade IV astrocytoma, is the most common primary neoplasm of the central nervous system (CNS) and has the highest malignancy and mortality rates. The invasive nature of GBM complicates surgical resection and restricts chemotherapeutic access, contributing to poor p...

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Detalles Bibliográficos
Autores principales: Zhao, Kai, Wang, Leilei, Li, Tao, Zhu, Meng, Zhang, Chen, Chen, Lei, Zhao, Pengfei, Zhou, Hua, Yu, Shengping, Yang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435333/
https://www.ncbi.nlm.nih.gov/pubmed/28440461
http://dx.doi.org/10.3892/ijo.2017.3973

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