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MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8(+) T cells and contributes to protection against infection
A number of nonclassical MHC Ib molecules recognizing distinct microbial antigens have been implicated in the immune response to Mycobacterium tuberculosis (Mtb). HLA-E has been identified to present numerous Mtb peptides to CD8(+) T cells, with multiple HLA-E-restricted cytotoxic T lymphocyte (CTL)...
Autores principales: | Bian, Yao, Shang, Shaobin, Siddiqui, Sarah, Zhao, Jie, Joosten, Simone A., Ottenhoff, Tom H. M., Cantor, Harvey, Wang, Chyung-Ru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435364/ https://www.ncbi.nlm.nih.gov/pubmed/28475642 http://dx.doi.org/10.1371/journal.ppat.1006384 |
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