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Placental O-GlcNAc-transferase expression and interactions with the glucocorticoid receptor are sex specific and regulated by maternal corticosterone exposure in mice

Maternal stress programs offspring disease in a sexually dimorphic manner with males often more adversely affected. Previous studies of maternal glucocorticoid exposure suggest male vulnerability may derive from placental alterations. The hexosamine signalling pathway and O-linked glycosylation (O-G...

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Detalles Bibliográficos
Autores principales: Pantaleon, Marie, Steane, Sarah E., McMahon, Kathryn, Cuffe, James S. M., Moritz, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435684/
https://www.ncbi.nlm.nih.gov/pubmed/28515473
http://dx.doi.org/10.1038/s41598-017-01666-8