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Placental O-GlcNAc-transferase expression and interactions with the glucocorticoid receptor are sex specific and regulated by maternal corticosterone exposure in mice
Maternal stress programs offspring disease in a sexually dimorphic manner with males often more adversely affected. Previous studies of maternal glucocorticoid exposure suggest male vulnerability may derive from placental alterations. The hexosamine signalling pathway and O-linked glycosylation (O-G...
Autores principales: | Pantaleon, Marie, Steane, Sarah E., McMahon, Kathryn, Cuffe, James S. M., Moritz, Karen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435684/ https://www.ncbi.nlm.nih.gov/pubmed/28515473 http://dx.doi.org/10.1038/s41598-017-01666-8 |
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