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Endocytic uptake of monomeric amyloid-β peptides is clathrin- and dynamin-independent and results in selective accumulation of Aβ(1–42) compared to Aβ(1–40)

Intraneuronal accumulation of amyloid-β (Aβ) peptides represent an early pathological feature in Alzheimer’s disease. We have therefore utilized flow cytometry and confocal microscopy in combination with endocytosis inhibition to explore the internalisation efficiency and uptake mechanisms of Aβ(1–4...

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Detalles Bibliográficos
Autores principales:	Wesén, Emelie, Jeffries, Gavin D. M., Matson Dzebo, Maria, Esbjörner, Elin K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435687/ https://www.ncbi.nlm.nih.gov/pubmed/28515429 http://dx.doi.org/10.1038/s41598-017-02227-9

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