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Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses

G-quadruplexes (G4s) are secondary structures of nucleic acids that epigenetically regulate cellular processes. In the human immunodeficiency lentivirus 1 (HIV-1), dynamic G4s are located in the unique viral LTR promoter. Folding of HIV-1 LTR G4s inhibits viral transcription; stabilization by G4 lig...

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Detalles Bibliográficos
Autores principales:	Perrone, Rosalba, Lavezzo, Enrico, Palù, Giorgio, Richter, Sara N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435695/ https://www.ncbi.nlm.nih.gov/pubmed/28515481 http://dx.doi.org/10.1038/s41598-017-02291-1

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