Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling

The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional status and survival. The underlying causes of cachexia are incompletely understo...

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Detalles Bibliográficos
Autores principales: Pettersen, Kristine, Andersen, Sonja, Degen, Simone, Tadini, Valentina, Grosjean, Joël, Hatakeyama, Shinji, Tesfahun, Almaz N., Moestue, Siver, Kim, Jana, Nonstad, Unni, Romundstad, Pål R., Skorpen, Frank, Sørhaug, Sveinung, Amundsen, Tore, Grønberg, Bjørn H., Strasser, Florian, Stephens, Nathan, Hoem, Dag, Molven, Anders, Kaasa, Stein, Fearon, Kenneth, Jacobi, Carsten, Bjørkøy, Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435723/
https://www.ncbi.nlm.nih.gov/pubmed/28515477
http://dx.doi.org/10.1038/s41598-017-02088-2

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