Cargando…

MiR-520b as a novel molecular target for suppressing stemness phenotype of head-neck cancer by inhibiting CD44

Cancer stem cells preferentially acquire the specific characteristics of stress tolerance and high mobility, allowing them to progress to a therapy-refractive state. To identify a critical molecule to regulate cancer stemness is indispensable to erratically cure cancer. In this study, we identified...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Ya-Ching, Cheng, Ann-Joy, Lee, Li-Yu, You, Guo-Rung, Li, Yan-Liang, Chen, Hsin-Ying, Chang, Joseph T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435724/ https://www.ncbi.nlm.nih.gov/pubmed/28515423 http://dx.doi.org/10.1038/s41598-017-02058-8

Ejemplares similares

CD44s and CD44v6 Expression in Head and Neck Epithelia
por: Mack, Brigitte, et al.
Publicado: (2008)

Hsa-miR-520d Converts Fibroblasts into CD105+ Populations
por: Ishihara, Yoshitaka, et al.
Publicado: (2014)

Systemic Investigation Identifying Salivary miR-196b as a Promising Biomarker for Early Detection of Head-Neck Cancer and Oral Precancer Lesions
por: Cheng, Ann-Joy, et al.
Publicado: (2021)

CD44s Induces miR-629-3p Expression in Association with Cisplatin Resistance in Head and Neck Cancer Cells
por: Chikuda, Junichiro, et al.
Publicado: (2020)

LncRNA ZFAS1 contributes to osteosarcoma progression via miR-520b and miR-520e-mediated inhibition of RHOC signaling
por: Liu, Xiaofeng, et al.
Publicado: (2022)

Multifaceted and Intricate Oncogenic Mechanisms of NDRG1 in Head and Neck Cancer Depend on Its C-Terminal 3R-Motif
por: You, Guo-Rung, et al.
Publicado: (2022)

LDL Receptor Pathway Regulation by miR-224 and miR-520d
por: Salerno, Alessandro G., et al.
Publicado: (2020)

GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway
por: Li, Yan-Liang, et al.
Publicado: (2016)

miR-302c-3p and miR-520a-3p suppress the proliferation of cervical carcinoma cells by targeting CXCL8
por: Ding, Hong-Mei, et al.
Publicado: (2021)

Characterization of CD44 variant expression in head and neck squamous cell carcinomas
por: Spiegelberg, D., et al.
Publicado: (2013)

Expression of CD44 in Head and Neck Squamous Cell Carcinoma—An In-Silico Study
por: Kavitha, Loganathan, et al.
Publicado: (2023)

Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses
por: You, Guo-Rung, et al.
Publicado: (2019)

Molecular Signature of Long Non-Coding RNA Associated with Areca Nut-Induced Head and Neck Cancer
por: Huang, Hung-Han, et al.
Publicado: (2023)

GATA6 suppresses migration and metastasis by regulating the miR-520b/CREB1 axis in gastric cancer
por: Liu, Hao, et al.
Publicado: (2019)

Circular RNA 0102049 suppresses the progression of osteosarcoma through modulating miR-520g-3p/PLK2 axis
por: Zhang, Xianliao, et al.
Publicado: (2021)

The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness
por: Chen, Hsin-Ying, et al.
Publicado: (2018)

MiR-520f acts as a biomarker for the diagnosis of lung cancer
por: Zhou, Yingyan, et al.
Publicado: (2019)

Role of miR-520b in non-small cell lung cancer
por: Zhang, Linlin, et al.
Publicado: (2018)

A CD44(high)/EGFR(low) Subpopulation within Head and Neck Cancer Cell Lines Shows an Epithelial-Mesenchymal Transition Phenotype and Resistance to Treatment
por: La Fleur, Linnea, et al.
Publicado: (2012)

Role of CD44 as a marker of cancer stem cells in head and neck cancer
por: Trapasso, Serena, et al.
Publicado: (2012)

Clinicopathological Significance of Expression of CD44 Variants in Head and Neck Squamous Cell Carcinoma
por: Kanke, Minoru, et al.
Publicado: (2000)

FGF16 regulated by miR-520b enhances the cell proliferation of lung cancer
por: He, Wenfeng, et al.
Publicado: (2021)

Correction to: GATA6 suppresses migration and metastasis by regulating the miR-520b/CREB1 axis in gastric cancer
por: Liu, Hao, et al.
Publicado: (2022)

Significance of CD44 expression in head and neck cancer: a systemic review and meta-analysis
por: Chen, Jianqiang, et al.
Publicado: (2014)

Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression
por: Rani, Bhavna, et al.
Publicado: (2018)

miR-520b Promotes Breast Cancer Stemness Through Hippo/YAP Signaling Pathway
por: Zhang, Hui, et al.
Publicado: (2019)

Targeting CD44v6 for fluorescence-guided surgery in head and neck squamous cell carcinoma
por: Odenthal, Julia, et al.
Publicado: (2018)

MiR‐520b restrains cell growth by targeting HDAC4 in lung cancer
por: Jin, Ke, et al.
Publicado: (2018)

Molecular Interplays Between Cell Invasion and Radioresistance That Lead to Poor Prognosis in Head-Neck Cancer
por: You, Guo-Rung, et al.
Publicado: (2021)

miR520a-3p suppresses cell proliferation and metastasis by inhibiting the p65–NFκB pathway in glioblastoma
por: Zhang, Jing-quan, et al.
Publicado: (2019)

Nitroxoline suppresses metastasis in bladder cancer via EGR1/circNDRG1/miR-520h/smad7/EMT signaling pathway
por: Ren, Liangliang, et al.
Publicado: (2022)

A Combined Systemic Strategy for Overcoming Cisplatin Resistance in Head and Neck Cancer: From Target Identification to Drug Discovery
por: Chen, Yin-Ju, et al.
Publicado: (2020)

MiR-520d-5p directly targets TWIST1 and downregulates the metastamiR miR-10b
por: Tsukerman, Pinchas, et al.
Publicado: (2014)

CD44v6-Targeted Imaging of Head and Neck Squamous Cell Carcinoma: Antibody-Based Approaches
por: Spiegelberg, Diana, et al.
Publicado: (2017)

The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer
por: Zhu, Qin, et al.
Publicado: (2021)

MiR-520d-3p suppresses the proliferation and epithelial-mesenchymal transition of cervical cancer cells by targeting ZFP36L2
por: Zhang, Yuan, et al.
Publicado: (2023)

Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor Metastasis
por: Lee, Younghee, et al.
Publicado: (2010)

520 CTSA Search Solutions
por: Tafuto, Barbara, et al.
Publicado: (2022)

PRRX1 Regulates Cellular Phenotype Plasticity and Dormancy of Head and Neck Squamous Cell Carcinoma Through miR-642b-3p()()
por: Jiang, Jian, et al.
Publicado: (2019)

MiR-125 family improves the radiosensitivity of head and neck squamous cell carcinoma
por: Wang, Qi-Wei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v0tb36bohdvid3bt7igg1vok4g