Cargando…

Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

The pathogenesis of osteoarthritis (OA) is poorly understood, and therapeutic approaches are limited to preventing progression of the disease. Recent studies have shown that exosomes play a vital role in cell-to-cell communication, and pathogenesis of many age-related diseases. Molecular profiling o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kolhe, Ravindra, Hunter, Monte, Liu, Siyang, Jadeja, Ravirajsinh N., Pundkar, Chetan, Mondal, Ashis K., Mendhe, Bharati, Drewry, Michelle, Rojiani, Mumtaz V., Liu, Yutao, Isales, Carlos M., Guldberg, Robert E., Hamrick, Mark W., Fulzele, Sadanand
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435729/ https://www.ncbi.nlm.nih.gov/pubmed/28515465 http://dx.doi.org/10.1038/s41598-017-01905-y

Ejemplares similares

Modulation of miRNAs by Vitamin C in Human Bone Marrow Stromal Cells
por: Kolhe, Ravindra, et al.
Publicado: (2018)

Sex-Specific Differences in Extracellular Vesicle Protein Cargo in Synovial Fluid of Patients with Osteoarthritis
por: Kolhe, Ravindra, et al.
Publicado: (2020)

Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics
por: Burke, John, et al.
Publicado: (2016)

Therapeutic potential of mesenchymal stem cell based therapy for osteoarthritis
por: Burke, John, et al.
Publicado: (2016)

Nanostring-Based Identification of the Gene Expression Profile in Trigger Finger Samples
por: Kolhe, Ravindra, et al.
Publicado: (2021)

Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells
por: Fulzele, Sadanand, et al.
Publicado: (2019)

Depletion of the miR-34a “sponge” MALAT1 in aging skeletal muscle: Implications for age-related muscle loss
por: Ruan, Ling, et al.
Publicado: (2021)

Synergistic Effects of Multiple Factors Involved in COVID-19-dependent Muscle Loss
por: Cantu, Nicholas, et al.
Publicado: (2022)

Alteration in Nasopharyngeal Microbiota Profile in Aged Patients with COVID-19
por: Kolhe, Ravindra, et al.
Publicado: (2021)

Very Long-Chain C24:1 Ceramide Is Increased in Serum Extracellular Vesicles with Aging and Can Induce Senescence in Bone-Derived Mesenchymal Stem Cells
por: Khayrullin, Andrew, et al.
Publicado: (2019)

Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss
por: Singleton, Quante, et al.
Publicado: (2019)

Extracellular vesicles in the pathogenesis of rheumatoid arthritis and osteoarthritis
por: Withrow, Joseph, et al.
Publicado: (2016)

Making a Difference: Adaptation of the Clinical Laboratory in Response to the Rapidly Evolving COVID-19 Pandemic
por: Sahajpal, Nikhil S., et al.
Publicado: (2021)

Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation
por: Kaiser, Helen, et al.
Publicado: (2019)

Long Non-coding RNA MALAT1 Is Depleted With Age in Skeletal Muscle in vivo and MALAT1 Silencing Increases Expression of TGF-β1 in vitro
por: Ruan, Ling, et al.
Publicado: (2022)

Delineating Pro-Angiogenic Myeloid Cells in Cancer Therapy
por: Johnson, Benjamin W., et al.
Publicado: (2018)

Identification and Clinical Validation of a Novel 4 Gene-Signature with Prognostic Utility in Colorectal Cancer
por: Ahluwalia, Pankaj, et al.
Publicado: (2019)

Infections of the lung: a predictive, preventive and personalized perspective through the lens of evolution, the emergence of SARS-CoV-2 and its pathogenesis
por: Ahluwalia, Pankaj, et al.
Publicado: (2020)

Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice
por: Pandya, Chirayu D., et al.
Publicado: (2019)

Inhibiting MicroRNA-141-3p Improves Musculoskeletal Health in Aged Mice
por: Vyavahare, Sagar, et al.
Publicado: (2023)

Proteomic Analysis of Female Synovial Fluid to Identify Novel Biomarkers for Osteoarthritis
por: Muller, P. Robinson, et al.
Publicado: (2023)

Prognostic and therapeutic implications of extracellular matrix associated gene signature in renal clear cell carcinoma
por: Ahluwalia, Pankaj, et al.
Publicado: (2021)

Immunogenomic Gene Signature of Cell-Death Associated Genes with Prognostic Implications in Lung Cancer
por: Ahluwalia, Pankaj, et al.
Publicado: (2021)

Natural Killer Cells and Dendritic Cells: Expanding Clinical Relevance in the Non-Small Cell Lung Cancer (NSCLC) Tumor Microenvironment
por: Ahluwalia, Pankaj, et al.
Publicado: (2021)

COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/Profile
por: Fulzele, Sadanand, et al.
Publicado: (2020)

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression
por: Mangaonkar, Abhishek, et al.
Publicado: (2017)

TIMP-1 downregulation modulates miR-125a-5p expression and triggers the apoptotic pathway
por: Ghoshal-Gupta, Sampa, et al.
Publicado: (2018)

Recent advances in hyaluronic acid based therapy for osteoarthritis
por: Bowman, Steven, et al.
Publicado: (2018)

Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview
por: Vyavahare, Sagar, et al.
Publicado: (2021)

Immune Factors Drive Expression of SARS-CoV-2 Receptor Genes Amid Sexual Disparity
por: Vashisht, Ashutosh, et al.
Publicado: (2023)

Clinical validation of a multiplex PCR-based detection assay using saliva or nasopharyngeal samples for SARS-Cov-2, influenza A and B
por: Sahajpal, Nikhil S., et al.
Publicado: (2022)

Advances in Adipose-Derived Stem Cells Isolation, Characterization, and Application in Regenerative Tissue Engineering
por: Wankhade, Umesh D., et al.
Publicado: (2016)

Clinical Validation of a Sensitive Test for Saliva Collected in Healthcare and Community Settings with Pooling Utility for Severe Acute Respiratory Syndrome Coronavirus 2 Mass Surveillance
por: Sahajpal, Nikhil S., et al.
Publicado: (2021)

Role of clinical laboratories in response to the COVID-19 pandemic
por: Sahajpal, Nikhil Shri, et al.
Publicado: (2020)

Infection and Immune Memory: Variables in Robust Protection by Vaccines Against SARS-CoV-2
por: Ahluwalia, Pankaj, et al.
Publicado: (2021)

TIMP-1-Mediated Chemoresistance via Induction of IL-6 in NSCLC
por: Xiao, Wei, et al.
Publicado: (2019)

Low level of Vitamin C and dysregulation of Vitamin C transporter might be involved in the severity of COVID-19 Infection
por: Patterson, Taylor, et al.
Publicado: (2021)

SalivaSTAT: Direct-PCR and Pooling of Saliva Samples Collected in Healthcare and Community Setting for SARS-CoV-2 Mass Surveillance
por: Sahajpal, Nikhil S., et al.
Publicado: (2021)

Stromal cell-derived factor-1 as a potential therapeutic target for osteoarthritis and rheumatoid arthritis
por: Bragg, Robert, et al.
Publicado: (2019)

A 3-Week Tryptophan-Deficient Diet Resulted in Decreased Body Weight and Increased Trabecular Bone Mass in Mice
por: Isales, Carlos, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i6d2f0gasi27ul94ca0k0pgcjc