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Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression
Mitochondrial respiration plays a crucial role in determining the metabolic state of brown adipose tissue (BAT), due to its direct roles in thermogenesis, as well as through additional mechanisms. Here, we show that respiration-dependent retrograde signaling from mitochondria to nucleus contributes...
Autores principales: | Nam, Minwoo, Akie, Thomas E., Sanosaka, Masato, Craige, Siobhan M., Kant, Shashi, Keaney Jr, John F., Cooper, Marcus P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435730/ https://www.ncbi.nlm.nih.gov/pubmed/28515438 http://dx.doi.org/10.1038/s41598-017-01879-x |
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