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Photolysis of Caged-GABA Rapidly Terminates Seizures In Vivo: Concentration and Light Intensity Dependence

The therapy of focal epilepsy remains unsatisfactory for as many as 25% of patients. The photolysis of caged-γ-aminobutyric acid (caged-GABA) represents a novel and alternative option for the treatment of intractable epilepsy. Our previous experimental results have demonstrated that the use of blue...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Yu, Zhixin, Yan, Jiaqing, Xue, Fenqin, Ren, Guoping, Jiang, Chenxi, Wang, Weimin, Piao, Yueshan, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435768/
https://www.ncbi.nlm.nih.gov/pubmed/28572790
http://dx.doi.org/10.3389/fneur.2017.00215

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