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The dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin functions as antioxidant on human endothelial cells exposed to chronic hyperglycemia and metabolic high-glucose memory

Dipeptidyl peptidase-4 inhibitors are widely used in type 2 diabetes. Endothelium plays a crucial role maintaining vascular integrity and function. Chronic exposure to high glucose drives to endothelial dysfunction generating oxidative stress. Teneligliptin is a novel dipeptidyl peptidase-4 inhibito...

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Detalles Bibliográficos
Autores principales: Pujadas, Gemma, De Nigris, Valeria, Prattichizzo, Francesco, La Sala, Lucia, Testa, Roberto, Ceriello, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435779/
https://www.ncbi.nlm.nih.gov/pubmed/27530507
http://dx.doi.org/10.1007/s12020-016-1052-0