Comprehensive processing of high-throughput small RNA sequencing data including quality checking, normalization, and differential expression analysis using the UEA sRNA Workbench

Recently, high-throughput sequencing (HTS) has revealed compelling details about the small RNA (sRNA) population in eukaryotes. These 20 to 25 nt noncoding RNAs can influence gene expression by acting as guides for the sequence-specific regulatory mechanism known as RNA silencing. The increase in se...

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Detalles Bibliográficos
Autores principales: Beckers, Matthew, Mohorianu, Irina, Stocks, Matthew, Applegate, Christopher, Dalmay, Tamas, Moulton, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435855/
https://www.ncbi.nlm.nih.gov/pubmed/28289155
http://dx.doi.org/10.1261/rna.059360.116

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