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Single-cell transcriptomics reveals specific RNA editing signatures in the human brain
While RNA editing by A-to-I deamination is a requisite for neuronal function in humans, it is under-investigated in single cells. Here we fill this gap by analyzing RNA editing profiles of single cells from the brain cortex of living human subjects. We show that RNA editing levels per cell are bimod...
Autores principales: | Picardi, Ernesto, Horner, David S., Pesole, Graziano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435858/ https://www.ncbi.nlm.nih.gov/pubmed/28258159 http://dx.doi.org/10.1261/rna.058271.116 |
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