Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain

Spliceosomal proteins Hsh49p and Cus1p are components of SF3b, which together with SF3a, Msl1p/Lea1p, Sm proteins, and U2 snRNA, form U2 snRNP, which plays a crucial role in pre-mRNA splicing. Hsh49p, comprising two RRMs, forms a heterodimer with Cus1p. We determined the crystal structures of Saccha...

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Detalles Bibliográficos
Autores principales: van Roon, Anne-Marie M., Oubridge, Chris, Obayashi, Eiji, Sposito, Benedetta, Newman, Andrew J., Séraphin, Bertrand, Nagai, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435868/
https://www.ncbi.nlm.nih.gov/pubmed/28348170
http://dx.doi.org/10.1261/rna.059378.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435868/
https://www.ncbi.nlm.nih.gov/pubmed/28348170
http://dx.doi.org/10.1261/rna.059378.116

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