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Sleep supports inhibitory operant conditioning memory in Aplysia
Sleep supports memory consolidation as shown in mammals and invertebrates such as bees and Drosophila. Here, we show that sleep's memory function is preserved in Aplysia californica with an even simpler nervous system. Animals performed on an inhibitory conditioning task (“learning that a food...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435883/ https://www.ncbi.nlm.nih.gov/pubmed/28507034 http://dx.doi.org/10.1101/lm.045054.117 |
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author | Vorster, Albrecht P. A. Born, Jan |
author_facet | Vorster, Albrecht P. A. Born, Jan |
author_sort | Vorster, Albrecht P. A. |
collection | PubMed |
description | Sleep supports memory consolidation as shown in mammals and invertebrates such as bees and Drosophila. Here, we show that sleep's memory function is preserved in Aplysia californica with an even simpler nervous system. Animals performed on an inhibitory conditioning task (“learning that a food is inedible”) three times, at Training, Retrieval 1, and Retrieval 2, with 17-h intervals between tests. Compared with Wake animals, remaining awake between Training and Retrieval 1, Sleep animals with undisturbed post-training sleep, performed significantly better at Retrieval 1 and 2. Control experiments testing retrieval only after ∼34 h, confirmed the consolidating effect of sleep occurring within 17 h after training. |
format | Online Article Text |
id | pubmed-5435883 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Cold Spring Harbor Laboratory Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-54358832017-06-02 Sleep supports inhibitory operant conditioning memory in Aplysia Vorster, Albrecht P. A. Born, Jan Learn Mem Brief Communication Sleep supports memory consolidation as shown in mammals and invertebrates such as bees and Drosophila. Here, we show that sleep's memory function is preserved in Aplysia californica with an even simpler nervous system. Animals performed on an inhibitory conditioning task (“learning that a food is inedible”) three times, at Training, Retrieval 1, and Retrieval 2, with 17-h intervals between tests. Compared with Wake animals, remaining awake between Training and Retrieval 1, Sleep animals with undisturbed post-training sleep, performed significantly better at Retrieval 1 and 2. Control experiments testing retrieval only after ∼34 h, confirmed the consolidating effect of sleep occurring within 17 h after training. Cold Spring Harbor Laboratory Press 2017-06 /pmc/articles/PMC5435883/ /pubmed/28507034 http://dx.doi.org/10.1101/lm.045054.117 Text en © 2017 Vorster and Born; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article, published in Learning & Memory, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Brief Communication Vorster, Albrecht P. A. Born, Jan Sleep supports inhibitory operant conditioning memory in Aplysia |
title | Sleep supports inhibitory operant conditioning memory in Aplysia |
title_full | Sleep supports inhibitory operant conditioning memory in Aplysia |
title_fullStr | Sleep supports inhibitory operant conditioning memory in Aplysia |
title_full_unstemmed | Sleep supports inhibitory operant conditioning memory in Aplysia |
title_short | Sleep supports inhibitory operant conditioning memory in Aplysia |
title_sort | sleep supports inhibitory operant conditioning memory in aplysia |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435883/ https://www.ncbi.nlm.nih.gov/pubmed/28507034 http://dx.doi.org/10.1101/lm.045054.117 |
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