A guide for targeted SUMO removal

SUMO homeostasis is important for many cellular processes. In the current issue of Genes & Development, Liang and colleagues (pp. 802–815) demonstrate how a desumoylation enzyme is targeted to the nucleolus for removing SUMO from specific substrates and how curtailing sumoylation levels can regu...

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Detalles Bibliográficos
Autores principales: Dhingra, Nalini, Zhao, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Outlook
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435885/
https://www.ncbi.nlm.nih.gov/pubmed/28512234
http://dx.doi.org/10.1101/gad.300491.117
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author Dhingra, Nalini
Zhao, Xiaolan
author_facet Dhingra, Nalini
Zhao, Xiaolan
author_sort Dhingra, Nalini
collection PubMed
description SUMO homeostasis is important for many cellular processes. In the current issue of Genes & Development, Liang and colleagues (pp. 802–815) demonstrate how a desumoylation enzyme is targeted to the nucleolus for removing SUMO from specific substrates and how curtailing sumoylation levels can regulate transcription in this nuclear compartment.
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spelling pubmed-54358852017-10-15 A guide for targeted SUMO removal Dhingra, Nalini Zhao, Xiaolan Genes Dev Outlook SUMO homeostasis is important for many cellular processes. In the current issue of Genes & Development, Liang and colleagues (pp. 802–815) demonstrate how a desumoylation enzyme is targeted to the nucleolus for removing SUMO from specific substrates and how curtailing sumoylation levels can regulate transcription in this nuclear compartment. Cold Spring Harbor Laboratory Press 2017-04-15 /pmc/articles/PMC5435885/ /pubmed/28512234 http://dx.doi.org/10.1101/gad.300491.117 Text en © 2017 Dhingra and Zhao; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Outlook
Dhingra, Nalini
Zhao, Xiaolan
A guide for targeted SUMO removal
title A guide for targeted SUMO removal
title_full A guide for targeted SUMO removal
title_fullStr A guide for targeted SUMO removal
title_full_unstemmed A guide for targeted SUMO removal
title_short A guide for targeted SUMO removal
title_sort guide for targeted sumo removal
topic Outlook
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435885/
https://www.ncbi.nlm.nih.gov/pubmed/28512234
http://dx.doi.org/10.1101/gad.300491.117
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