Cargando…

p27(Kip1), PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes

The cyclin-dependent kinase inhibitor p27(Kip1) (p27) also behaves as a transcriptional repressor. Data showing that the p300/CBP-associated factor (PCAF) acetylates p27 inducing its degradation suggested that PCAF and p27 could collaborate in the regulation of transcription. However, this possibili...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perearnau, Anna, Orlando, Serena, Islam, Abul B.M.M.K., Gallastegui, Edurne, Martínez, Jonatan, Jordan, Albert, Bigas, Anna, Aligué, Rosa, Pujol, Maria Jesús, Bachs, Oriol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435914/ https://www.ncbi.nlm.nih.gov/pubmed/28158851 http://dx.doi.org/10.1093/nar/gkx075

Ejemplares similares

PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27(Kip1)
por: Pérez-Luna, Maria, et al.
Publicado: (2012)

p27(Kip1) and p21(Cip1) collaborate in the regulation of transcription by recruiting cyclin–Cdk complexes on the promoters of target genes
por: Orlando, Serena, et al.
Publicado: (2015)

The transcriptional co-activator PCAF regulates cdk2 activity
por: Mateo, Francesca, et al.
Publicado: (2009)

Role of p27(Kip1) as a transcriptional regulator
por: Bachs, Oriol, et al.
Publicado: (2018)

ChIP-Seq analysis identifies p27(Kip1)-target genes involved in cell adhesion and cell signalling in mouse embryonic fibroblasts
por: Biçer, Atilla, et al.
Publicado: (2017)

p27(Kip1) regulates alpha-synuclein expression
por: Gallastegui, Edurne, et al.
Publicado: (2018)

PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription
por: Lew, Qiao Jing, et al.
Publicado: (2011)

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression
por: Wan, Junhu, et al.
Publicado: (2015)

PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6
por: Wan, Junhu, et al.
Publicado: (2016)

The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt–PCAF pathway in promotion of esophageal squamous cell carcinoma growth
por: Wu, Yue, et al.
Publicado: (2020)

MyoD regulates p57(kip2) expression by interacting with a distant cis-element and modifying a higher order chromatin structure
por: Busanello, Anna, et al.
Publicado: (2012)

Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development
por: Sun, Jian, et al.
Publicado: (2015)

PAUPAR and PAX6 sequentially regulate human embryonic stem cell cortical differentiation
por: Xu, Yanxin, et al.
Publicado: (2021)

Pax7 pioneer factor action requires both paired and homeo DNA binding domains
por: Pelletier, Audrey, et al.
Publicado: (2021)

Chromatin opening ability of pioneer factor Pax7 depends on unique isoform and C-terminal domain
por: Bascunana, Virginie, et al.
Publicado: (2023)

Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast
por: Cisneros-Barroso, Eugenia, et al.
Publicado: (2014)

DNA-mediated cooperativity facilitates the co-selection of cryptic enhancer sequences by SOX2 and PAX6 transcription factors
por: Narasimhan, Kamesh, et al.
Publicado: (2015)

NF-κB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas
por: Vento-Tormo, Roser, et al.
Publicado: (2014)

Fusarium BP1 is a reader of H3K27 methylation
por: Tang, Guangfei, et al.
Publicado: (2021)

The yeast prefoldin-like URI-orthologue Bud27 associates with the RSC nucleosome remodeler and modulates transcription
por: Mirón-García, María Carmen, et al.
Publicado: (2014)

Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association
por: Connelly, Katelyn E, et al.
Publicado: (2019)

PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation
por: Cohen, Lea R Z, et al.
Publicado: (2022)

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity
por: Young, Matthew D., et al.
Publicado: (2011)

The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification
por: Ullius, Andrea, et al.
Publicado: (2014)

CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin
por: Weth, Oliver, et al.
Publicado: (2014)

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
por: Pasini, Diego, et al.
Publicado: (2010)

Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells
por: Tak, Yu Gyoung, et al.
Publicado: (2016)

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes
por: Choi, Si Ho, et al.
Publicado: (2016)

The DNA dioxygenase Tet1 regulates H3K27 modification and embryonic stem cell biology independent of its catalytic activity
por: Chrysanthou, Stephanie, et al.
Publicado: (2022)

A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
por: Fan, Huitao, et al.
Publicado: (2021)

Lysine 27 dimethylation of Drosophila linker histone dH1 contributes to heterochromatin organization independently of H3K9 methylation
por: Bernués, Jordi, et al.
Publicado: (2022)

WOX11 recruits a histone H3K27me3 demethylase to promote gene expression during shoot development in rice
por: Cheng, Saifeng, et al.
Publicado: (2018)

MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain
por: Thambirajah, Anita A., et al.
Publicado: (2012)

The H3K36me2 methyltransferase NSD1 modulates H3K27ac at active enhancers to safeguard gene expression
por: Fang, Yuan, et al.
Publicado: (2021)

The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium
por: Chan, Ngai Ting, et al.
Publicado: (2022)

Evaluating the impact of single nucleotide variants on transcription factor binding
por: Shi, Wenqiang, et al.
Publicado: (2016)

Coordinated changes in gene expression, H1 variant distribution and genome 3D conformation in response to H1 depletion
por: Serna-Pujol, Núria, et al.
Publicado: (2022)

H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma
por: Zhang, Erbao, et al.
Publicado: (2017)

Fibroblast growth factor 1 induced during myogenesis by a transcription–translation coupling mechanism
por: Conte, Caroline, et al.
Publicado: (2009)

Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis
por: Enoiu, Milica, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_65vruamd2221i9hjpdh0thhj96