Characterization of human telomere RNA G-quadruplex structures in vitro and in living cells using (19)F NMR spectroscopy

Human telomeric RNA has been identified as a key component of the telomere machinery. Recently, the growing evidence suggests that the telomeric RNA forms G-quadruplex structures to play an important role in telomere protection and regulation. In the present studies, we developed a (19)F NMR spectro...

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Detalles Bibliográficos
Autores principales: Bao, Hong-Liang, Ishizuka, Takumi, Sakamoto, Takashi, Fujimoto, Kenzo, Uechi, Tamayo, Kenmochi, Naoya, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435947/
https://www.ncbi.nlm.nih.gov/pubmed/28180296
http://dx.doi.org/10.1093/nar/gkx109

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