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Human BCDIN3D monomethylates cytoplasmic histidine transfer RNA

Human RNA methyltransferase BCDIN3D is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. Here, we show that cytoplasmic tRNA(His) is the primary target of BCDIN3D in human cells. Recombinant human BCDIN3D, expressed in Escherichia...

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Detalles Bibliográficos
Autores principales:	Martinez, Anna, Yamashita, Seisuke, Nagaike, Takashi, Sakaguchi, Yuriko, Suzuki, Tsutomu, Tomita, Kozo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435960/ https://www.ncbi.nlm.nih.gov/pubmed/28119416 http://dx.doi.org/10.1093/nar/gkx051

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