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Modeling complex patterns of differential DNA methylation that associate with gene expression changes

Numerous genomic studies are underway to determine which genes are abnormally regulated by DNA methylation in disease. However, we have a poor understanding of how disease-specific methylation changes affect expression. We thus developed an integrative analysis tool, Methylation-based Gene Expressio...

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Detalles Bibliográficos
Autores principales: Schlosberg, Christopher E., VanderKraats, Nathan D., Edwards, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435975/
https://www.ncbi.nlm.nih.gov/pubmed/28168293
http://dx.doi.org/10.1093/nar/gkx078

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