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Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system

Genome editing research of human ES/iPS cells has been accelerated by clustered regularly interspaced short palindromic repeats/CRISPR-associated 9 (CRISPR/Cas9) and transcription activator-like effector nucleases (TALEN) technologies. However, the efficiency of biallelic genetic engineering in tran...

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Detalles Bibliográficos
Autores principales:	Takayama, Kazuo, Igai, Keisuke, Hagihara, Yasuko, Hashimoto, Rina, Hanawa, Morifumi, Sakuma, Tetsushi, Tachibana, Masashi, Sakurai, Fuminori, Yamamoto, Takashi, Mizuguchi, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435997/ https://www.ncbi.nlm.nih.gov/pubmed/28334759 http://dx.doi.org/10.1093/nar/gkx130

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