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Ligand binding to 2΄-deoxyguanosine sensing riboswitch in metabolic context

The mfl-riboswitch is a transcriptional off-switch, which down-regulates expression of subunit β of ribonucleotide reductase in Mesoplasma florum upon 2΄-deoxyguanosine binding. We characterized binding of 2΄-deoxyguanosine to the mfl-aptamer domain (WT aptamer) and a sequence-stabilized aptamer (MT...

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Detalles Bibliográficos
Autores principales:	Kim, Yong-Boum, Wacker, Anna, von Laer, Karl, Rogov, Vladimir V., Suess, Beatrix, Schwalbe, Harald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435998/ https://www.ncbi.nlm.nih.gov/pubmed/28115631 http://dx.doi.org/10.1093/nar/gkx016

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