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Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report

We present a patient with colorectal metastases confined to the lungs and treated with multiple resections until this was not an option anymore, followed by stereotactic body radiation therapy until this option was drained. Then, the patient was successfully treated with multiple microwave ablations...

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Detalles Bibliográficos
Autores principales: Bäcklund, Magnus, Freedman, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436004/
https://www.ncbi.nlm.nih.gov/pubmed/28559824
http://dx.doi.org/10.1159/000468982
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author Bäcklund, Magnus
Freedman, Jacob
author_facet Bäcklund, Magnus
Freedman, Jacob
author_sort Bäcklund, Magnus
collection PubMed
description We present a patient with colorectal metastases confined to the lungs and treated with multiple resections until this was not an option anymore, followed by stereotactic body radiation therapy until this option was drained. Then, the patient was successfully treated with multiple microwave ablations combined with immunological activation targeting the programmed cell death 1 receptor (PD-1), possibly instigating a powerful abscopal effect. Techniques, doses, and radiological findings are presented.
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spelling pubmed-54360042017-05-30 Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report Bäcklund, Magnus Freedman, Jacob Case Rep Oncol Case Report We present a patient with colorectal metastases confined to the lungs and treated with multiple resections until this was not an option anymore, followed by stereotactic body radiation therapy until this option was drained. Then, the patient was successfully treated with multiple microwave ablations combined with immunological activation targeting the programmed cell death 1 receptor (PD-1), possibly instigating a powerful abscopal effect. Techniques, doses, and radiological findings are presented. S. Karger AG 2017-04-27 /pmc/articles/PMC5436004/ /pubmed/28559824 http://dx.doi.org/10.1159/000468982 Text en Copyright © 2017 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Bäcklund, Magnus
Freedman, Jacob
Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report
title Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report
title_full Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report
title_fullStr Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report
title_full_unstemmed Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report
title_short Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report
title_sort microwave ablation and immune activation in the treatment of recurrent colorectal lung metastases: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436004/
https://www.ncbi.nlm.nih.gov/pubmed/28559824
http://dx.doi.org/10.1159/000468982
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