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Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter
The aggregation promoter heparin is commonly used to study the aggregation kinetics and biophysical properties of protein amyloids. However, the underlying mechanism for amyloid promotion by heparin remains poorly understood. In the case of the neuropeptide β-endorphin that can reversibly adopt a fu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436042/ https://www.ncbi.nlm.nih.gov/pubmed/28067354 http://dx.doi.org/10.1039/c6cc09770g |