EZH2 alterations in follicular lymphoma: biological and clinical correlations

The histone methyltransferase EZH2 has an essential role in the development of follicular lymphoma (FL). Recurrent gain-of-function mutations in EZH2 have been described in 25% of FL patients and induce aberrant methylation of histone H3 lysine 27 (H3K27). We evaluated the role of EZH2 genomic gains...

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Detalles Bibliográficos
Autores principales: Huet, S, Xerri, L, Tesson, B, Mareschal, S, Taix, S, Mescam-Mancini, L, Sohier, E, Carrère, M, Lazarovici, J, Casasnovas, O, Tonon, L, Boyault, S, Hayette, S, Haioun, C, Fabiani, B, Viari, A, Jardin, F, Salles, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436075/
https://www.ncbi.nlm.nih.gov/pubmed/28430172
http://dx.doi.org/10.1038/bcj.2017.32

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