Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia

Although tyrosine kinase inhibitors (TKIs) have significantly improved the prognosis of chronic myeloid leukemia (CML), the ability of TKIs to eradicate CML remains uncertain and patients must continue TKI therapy for indefinite periods. In this study, we performed whole-exome sequencing to identify...

Descripción completa

Detalles Bibliográficos
Autores principales: Togasaki, E, Takeda, J, Yoshida, K, Shiozawa, Y, Takeuchi, M, Oshima, M, Saraya, A, Iwama, A, Yokote, K, Sakaida, E, Hirase, C, Takeshita, A, Imai, K, Okumura, H, Morishita, Y, Usui, N, Takahashi, N, Fujisawa, S, Shiraishi, Y, Chiba, K, Tanaka, H, Kiyoi, H, Ohnishi, K, Ohtake, S, Asou, N, Kobayashi, Y, Miyazaki, Y, Miyano, S, Ogawa, S, Matsumura, I, Nakaseko, C, Naoe, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436079/
https://www.ncbi.nlm.nih.gov/pubmed/28452984
http://dx.doi.org/10.1038/bcj.2017.36

Ejemplares similares

Ejemplares similares