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Synergistic antitumor effects of CDK inhibitor SNS-032 and an oncolytic adenovirus co-expressing TRAIL and Smac in pancreatic cancer

Gene therapy using oncolytic adenoviruses is a novel approach for human cancer therapeutics. The current study aimed to investigate whether the combined use of an adenovirus expressing tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and second mitochondria-derived activator of caspas...

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Detalles Bibliográficos
Autores principales: Ge, Yun, Lei, Wen, Ma, Yingyu, Wang, Yigang, Wei, Buyun, Chen, Xiaoyi, Ru, Guoqing, He, Xianglei, Mou, Xiaozhou, Wang, Shibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436152/
https://www.ncbi.nlm.nih.gov/pubmed/28440486
http://dx.doi.org/10.3892/mmr.2017.6472