Cargando…

Ginsenoside Rh2 and Rg3 inhibit cell proliferation and induce apoptosis by increasing mitochondrial reactive oxygen species in human leukemia Jurkat cells

Ginsenoside Rh2 (GRh2) and ginsenoside Rg3 (GRg3) are primary bioactive components in Panax ginseng. The present study aimed to investigate the underlying mechanisms of apoptotic cell-death induced by GRh2 and GRg3 in human leukemia Jurkat cells. The Cell Counting kit-8 assay was used to determine c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Ting, Wang, Ying-Nan, Zhou, Chuan-Xin, Wu, Li-Mei, Liu, Yong, Zeng, Qian-Hong, Zhang, Xiang-Long, Yao, Jia-Hui, Wang, Min, Fang, Jian-Pei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436158/ https://www.ncbi.nlm.nih.gov/pubmed/28440403 http://dx.doi.org/10.3892/mmr.2017.6459

Ejemplares similares

Neuroprotective effects of ginsenosides Rh(1 )and Rg(2 )on neuronal cells
por: Li, Xiao-Fan, et al.
Publicado: (2011)

Ginsenoside Rg3 Suppresses Proliferation and Induces Apoptosis in Human Osteosarcoma
por: Li, Yi, et al.
Publicado: (2018)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Knockdown of the Hippo transducer YAP reduces proliferation and promotes apoptosis in the Jurkat leukemia cell
por: Wu, Ran, et al.
Publicado: (2018)

Effect of Ginsenoside Rg3 on Apoptosis in Human Malignant Melanoma Cells
por: Lee, Hyun Seung, et al.
Publicado: (2020)

Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis
por: LI, HUI, et al.
Publicado: (2014)

Ginsenoside Rh2 stimulates the production of mitochondrial reactive oxygen species and induces apoptosis of cervical cancer cells by inhibiting mitochondrial electron transfer chain complex
por: Liu, Ying, et al.
Publicado: (2021)

Biotransformation of ginsenosides Rb(1), Rg(3 )and Rh(2 )in rat gastrointestinal tracts
por: Qian, Tianxiu, et al.
Publicado: (2010)

20(S)-Ginsenoside Rg3 Promotes HeLa Cell Apoptosis by Regulating Autophagy
por: Bian, Shuai, et al.
Publicado: (2019)

Apoptosis-Inducing Effect of Ginsenoside Rg6 on Human Lymphocytoma JK Cells
por: Chen, Bin, et al.
Publicado: (2013)

Effects of ginsenoside Rg3 on apoptosis in A375.S2 melanoma cells
por: Kim, Joo Hyoung, et al.
Publicado: (2019)

Ginsenoside-Rg5 induces apoptosis and DNA damage in human cervical cancer cells
por: LIANG, LI-DAN, et al.
Publicado: (2015)

Ginsenoside Rg2 Promotes the Proliferation and Stemness Maintenance of Porcine Mesenchymal Stem Cells through Autophagy Induction
por: Che, Lina, et al.
Publicado: (2023)

Mir-55 inhibition can reduce cell proliferation and induce apoptosis in Jurkat (Acute T cell Leukemia) cell line
por: Alizadeh, Sh, et al.
Publicado: (2014)

Ginsenoside Rg1 suppresses cancer cell proliferation through perturbing mitotic progression
por: Hong, Jihee, et al.
Publicado: (2022)

Morphine dependence is attenuated by red ginseng extract and ginsenosides Rh2, Rg3, and compound K
por: Yayeh, Taddesse, et al.
Publicado: (2016)

Opium Induces Apoptosis in Jurkat Cells
por: Igder, Somayeh, et al.
Publicado: (2013)

Induction of apoptosis in prostate cancer by ginsenoside Rh2
por: Tong-Lin Wu, Tony, et al.
Publicado: (2018)

Ginsenoside Rg(3) Induces Apoptosis of Human Breast Cancer (MDA-MB-231) Cells
por: Kim, Bo-Min, et al.
Publicado: (2013)

Ginsenoside Rg3 induces apoptosis and inhibits proliferation by down-regulating TIGAR in rats with gastric precancerous lesions
por: Lv, Shangbin, et al.
Publicado: (2022)

Inhibition of in vitro Tumor Cell Invasion by Ginsenoside Rg(3)
por: Shinkai, Kiyoko, et al.
Publicado: (1996)

Upregulation of autophagy by Ginsenoside Rg2 in MCF-7 cells
por: Chung, Yuheon, et al.
Publicado: (2018)

Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells
por: He, Fang, et al.
Publicado: (2020)

Effects of ginsenosides Re and Rg3 on intracellular redox state and cell proliferation in C6 glioma cells
por: Ng, Wai Yee, et al.
Publicado: (2008)

20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway
por: Zhang, Fei, et al.
Publicado: (2015)

Correction: Ginsenoside Rg3 induces apoptosis and inhibits proliferation by down-regulating TIGAR in rats with gastric precancerous lesions
por: Lv, Shangbin, et al.
Publicado: (2023)

Ginsenoside Rh2 represses autophagy to promote cervical cancer cell apoptosis during starvation
por: Wang, Jiawen, et al.
Publicado: (2020)

Ginsenoside Rg1 and 20(S)-Rg3 Induce IgA Production by Mouse B Cells
por: Park, Ha-Yan, et al.
Publicado: (2015)

Apoptosis is associated with triacylglycerol accumulation in Jurkat T-cells
por: Al-Saffar, N M S, et al.
Publicado: (2002)

Apoptosis-inducing effects of jujube (Zǎo) seed extracts on human Jurkat leukemia T cells
por: Taechakulwanijya, Natthanan, et al.
Publicado: (2016)

Effects of ginsenoside Rg1 on proliferation and directed differentiation of human umbilical cord mesenchymal stem cells into neural stem cells
por: Xiao, Li, et al.
Publicado: (2022)

Anti-Angiogenic Properties of Ginsenoside Rg3
por: Nakhjavani, Maryam, et al.
Publicado: (2020)

Pharmacological activities of ginsenoside Rg5 (Review)
por: Liu, Ming-Yang, et al.
Publicado: (2021)

Protective effect and mechanism of ginsenoside Rg2 on atherosclerosis
por: Xue, Qianqian, et al.
Publicado: (2023)

Synergistic effect of ginsenoside Rg3 with verapamil on the modulation of multidrug resistance in human acute myeloid leukemia cells
por: KIM, SUNG SU, et al.
Publicado: (2014)

Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage
por: Ni, X.J., et al.
Publicado: (2017)

Effects of ginsenoside Rg3 on epigenetic modification in ovarian cancer cells
por: Zhao, Lingqin, et al.
Publicado: (2019)

Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway
por: Zhao, Fang, et al.
Publicado: (2023)

Ginsenoside Rg3 stereoisomers differentially inhibit vascular smooth muscle cell proliferation and migration in diabetic atherosclerosis
por: Guo, Mengqi, et al.
Publicado: (2018)

Ginsenoside Rg3 Suppresses Palmitate-Induced Apoptosis in MIN6N8 Pancreatic β-Cells
por: Kim, Kyong, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_jsvhvq4vssgoclgsqjqbqk77lc