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Neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury

Mild to severe traumatic brain injuries have lasting effects on everyday functioning. Issues relating to sensory problems are often overlooked or not addressed until well after the onset of the injury. In particular, vision problems related to ambient vision and the magnocellular pathway often resul...

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Autores principales: Hudac, Caitlin M, Kota, Srinivas, Nedrow, James L, Molfese, Dennis L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436188/
https://www.ncbi.nlm.nih.gov/pubmed/28539777
http://dx.doi.org/10.2147/EB.S27290
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author Hudac, Caitlin M
Kota, Srinivas
Nedrow, James L
Molfese, Dennis L
author_facet Hudac, Caitlin M
Kota, Srinivas
Nedrow, James L
Molfese, Dennis L
author_sort Hudac, Caitlin M
collection PubMed
description Mild to severe traumatic brain injuries have lasting effects on everyday functioning. Issues relating to sensory problems are often overlooked or not addressed until well after the onset of the injury. In particular, vision problems related to ambient vision and the magnocellular pathway often result in posttrauma vision syndrome or visual midline shift syndrome. Symptoms from these syndromes are not restricted to the visual domain. Patients commonly experience proprioceptive, kinesthetic, vestibular, cognitive, and language problems. Neurooptometric rehabilitation often entails the use of corrective lenses, prisms, and binasal occlusion to accommodate the unstable magnocellular system. However, little is known regarding the neural mechanisms engaged during neurooptometric rehabilitation, nor how these mechanisms impact other domains. Event-related potentials from noninvasive electrophysiological recordings can be used to assess rehabilitation progress in patients. In this case report, high-density visual event-related potentials were recorded from one patient with posttrauma vision syndrome and secondary visual midline shift syndrome during a pattern reversal task, both with and without prisms. Results indicate that two factors occurring during the end portion of the P148 component (168–256 milliseconds poststimulus onset) map onto two separate neural systems that were engaged with and without neurooptometric rehabilitation. Without prisms, neural sources within somatosensory, language, and executive brain regions engage inefficient magnocellular system processing. However, when corrective prisms were worn, primary visual areas were appropriately engaged. The impact of using early neurooptometric rehabilitation for posttrauma vision syndrome, visual midline shift syndrome, and other similar subtle vision disorders to support neural reorganization is discussed.
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spelling pubmed-54361882017-05-24 Neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury Hudac, Caitlin M Kota, Srinivas Nedrow, James L Molfese, Dennis L Eye Brain Original Research Mild to severe traumatic brain injuries have lasting effects on everyday functioning. Issues relating to sensory problems are often overlooked or not addressed until well after the onset of the injury. In particular, vision problems related to ambient vision and the magnocellular pathway often result in posttrauma vision syndrome or visual midline shift syndrome. Symptoms from these syndromes are not restricted to the visual domain. Patients commonly experience proprioceptive, kinesthetic, vestibular, cognitive, and language problems. Neurooptometric rehabilitation often entails the use of corrective lenses, prisms, and binasal occlusion to accommodate the unstable magnocellular system. However, little is known regarding the neural mechanisms engaged during neurooptometric rehabilitation, nor how these mechanisms impact other domains. Event-related potentials from noninvasive electrophysiological recordings can be used to assess rehabilitation progress in patients. In this case report, high-density visual event-related potentials were recorded from one patient with posttrauma vision syndrome and secondary visual midline shift syndrome during a pattern reversal task, both with and without prisms. Results indicate that two factors occurring during the end portion of the P148 component (168–256 milliseconds poststimulus onset) map onto two separate neural systems that were engaged with and without neurooptometric rehabilitation. Without prisms, neural sources within somatosensory, language, and executive brain regions engage inefficient magnocellular system processing. However, when corrective prisms were worn, primary visual areas were appropriately engaged. The impact of using early neurooptometric rehabilitation for posttrauma vision syndrome, visual midline shift syndrome, and other similar subtle vision disorders to support neural reorganization is discussed. Dove Medical Press 2012-01-18 /pmc/articles/PMC5436188/ /pubmed/28539777 http://dx.doi.org/10.2147/EB.S27290 Text en © 2012 Hudac et al, publisher and licensee Dove Medical Press Ltd The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Hudac, Caitlin M
Kota, Srinivas
Nedrow, James L
Molfese, Dennis L
Neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury
title Neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury
title_full Neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury
title_fullStr Neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury
title_full_unstemmed Neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury
title_short Neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury
title_sort neural mechanisms underlying neurooptometric rehabilitation following traumatic brain injury
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436188/
https://www.ncbi.nlm.nih.gov/pubmed/28539777
http://dx.doi.org/10.2147/EB.S27290
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