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Senescent tumor cells lead the collective invasion in thyroid cancer

Cellular senescence has been perceived as a barrier against carcinogenesis. However, the senescence-associated secretory phenotype (SASP) of senescent cells can promote tumorigenesis. Here, we show senescent tumour cells are frequently present in the front region of collective invasion of papillary...

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Detalles Bibliográficos
Autores principales: Kim, Young Hwa, Choi, Yong Won, Lee, Jeonghun, Soh, Euy Young, Kim, Jang-Hee, Park, Tae Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436223/
https://www.ncbi.nlm.nih.gov/pubmed/28489070
http://dx.doi.org/10.1038/ncomms15208