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Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and renal fibrosis in 5/6-nephrectomized rats
Renal fibrosis is the final common pathway of all progressive renal disease. Excessive and chronic activation of the Wnt/β-catenin signaling pathway results in chronic kidney disease (CKD) progression. To mimic CKD, the present study used 5/6-nephrectomized rats, and alterations in kidney histology,...
Autores principales: | Lin, Xin, Zha, Yan, Zeng, Xiang-Zhen, Dong, Rong, Wang, Qing-Hua, Wang, Dong-Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436235/ https://www.ncbi.nlm.nih.gov/pubmed/28440442 http://dx.doi.org/10.3892/mmr.2017.6461 |
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