Cargando…
Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI
The neurotrophin brain-derived neurotrophic factor (BDNF) acts via tropomyosin-related kinase B receptor (TrkB) to regulate synapse maintenance and function in the neuromuscular system. The potentiation of acetylcholine (ACh) release by BDNF requires TrkB phosphorylation and Protein Kinase C (PKC) a...
Autores principales: | Hurtado, Erica, Cilleros, Víctor, Nadal, Laura, Simó, Anna, Obis, Teresa, Garcia, Neus, Santafé, Manel M., Tomàs, Marta, Halievski, Katherine, Jordan, Cynthia L., Lanuza, Maria A., Tomàs, Josep |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436293/ https://www.ncbi.nlm.nih.gov/pubmed/28572757 http://dx.doi.org/10.3389/fnmol.2017.00147 |
Ejemplares similares
-
BDNF-TrkB Signaling Coupled to nPKCε and cPKCβI Modulate the Phosphorylation of the Exocytotic Protein Munc18-1 During Synaptic Activity at the Neuromuscular Junction
por: Simó, Anna, et al.
Publicado: (2018) -
Opposed Actions of PKA Isozymes (RI and RII) and PKC Isoforms (cPKCβI and nPKCε) in Neuromuscular Developmental Synapse Elimination
por: Garcia, Neus, et al.
Publicado: (2019) -
The Impact of Kinases in Amyotrophic Lateral Sclerosis at the Neuromuscular Synapse: Insights into BDNF/TrkB and PKC Signaling
por: Lanuza, Maria A., et al.
Publicado: (2019) -
cPKC regulates interphase nuclear size during Xenopus development
por: Edens, Lisa J., et al.
Publicado: (2014) -
Statin-specific inhibition of Rab-GTPase regulates cPKC-mediated IKs internalization
por: Ronzier, Elsa, et al.
Publicado: (2019)