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Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus

BACKGROUND: The aim of this study was to evaluate the safety and clinical outcome of primary total knee arthroplasty in patients with diabetes mellitus. MATERIAL/METHODS: Among the patients who were treated with total knee arthroplasty, there were 98 patients (116 knees) associated with diabetes. Os...

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Autores principales: Liu, Pengcheng, Liu, Junfeng, Xia, Kuo, Chen, Liyang, Wu, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436413/
https://www.ncbi.nlm.nih.gov/pubmed/28484205
http://dx.doi.org/10.12659/MSM.901720
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author Liu, Pengcheng
Liu, Junfeng
Xia, Kuo
Chen, Liyang
Wu, Xing
author_facet Liu, Pengcheng
Liu, Junfeng
Xia, Kuo
Chen, Liyang
Wu, Xing
author_sort Liu, Pengcheng
collection PubMed
description BACKGROUND: The aim of this study was to evaluate the safety and clinical outcome of primary total knee arthroplasty in patients with diabetes mellitus. MATERIAL/METHODS: Among the patients who were treated with total knee arthroplasty, there were 98 patients (116 knees) associated with diabetes. Osteoarthritis was diagnosed in 90 patients and rheumatoid arthritis was diagnosed in 8 patients. Various degrees of preoperative knee deformities were found in 82 knees. The average fasting blood glucose was 9.8±3.6 mmol/L at admission. RESULTS: The clinical efficacy of TKA was satisfactory in patients with diabetes mellitus. Diabetic patients do not seem to have a significantly higher risk for infection and DVT after TKA. At the final follow-up time point, no prosthesis loosening was found and no revision was needed in any patients. The mean HSS scores increased and the excellent rate was 100%. CONCLUSIONS: Using perioperative comprehensive assessment of heart and lung function, and by preventing infection and the formation of DVT, we achieved satisfactory early clinical efficacy of TKA in patients with diabetes mellitus.
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spelling pubmed-54364132017-05-24 Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus Liu, Pengcheng Liu, Junfeng Xia, Kuo Chen, Liyang Wu, Xing Med Sci Monit Clinical Research BACKGROUND: The aim of this study was to evaluate the safety and clinical outcome of primary total knee arthroplasty in patients with diabetes mellitus. MATERIAL/METHODS: Among the patients who were treated with total knee arthroplasty, there were 98 patients (116 knees) associated with diabetes. Osteoarthritis was diagnosed in 90 patients and rheumatoid arthritis was diagnosed in 8 patients. Various degrees of preoperative knee deformities were found in 82 knees. The average fasting blood glucose was 9.8±3.6 mmol/L at admission. RESULTS: The clinical efficacy of TKA was satisfactory in patients with diabetes mellitus. Diabetic patients do not seem to have a significantly higher risk for infection and DVT after TKA. At the final follow-up time point, no prosthesis loosening was found and no revision was needed in any patients. The mean HSS scores increased and the excellent rate was 100%. CONCLUSIONS: Using perioperative comprehensive assessment of heart and lung function, and by preventing infection and the formation of DVT, we achieved satisfactory early clinical efficacy of TKA in patients with diabetes mellitus. International Scientific Literature, Inc. 2017-05-09 /pmc/articles/PMC5436413/ /pubmed/28484205 http://dx.doi.org/10.12659/MSM.901720 Text en © Med Sci Monit, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Liu, Pengcheng
Liu, Junfeng
Xia, Kuo
Chen, Liyang
Wu, Xing
Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus
title Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus
title_full Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus
title_fullStr Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus
title_full_unstemmed Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus
title_short Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus
title_sort clinical outcome evaluation of primary total knee arthroplasty in patients with diabetes mellitus
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436413/
https://www.ncbi.nlm.nih.gov/pubmed/28484205
http://dx.doi.org/10.12659/MSM.901720
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