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The antihelminthic drug niclosamide effectively inhibits the malignant phenotypes of uveal melanoma in vitro and in vivo

Uveal melanoma (UM) is a lethal intraocular malignancy with an average survival of only 2~8 months in patients with hepatic metastasis. Currently, there is no effective therapy for metastatic UM. Here, we reported that niclosamide, an effective repellence of tapeworm that has been approved for use i...

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Detalles Bibliográficos
Autores principales: Zhou, Jingfeng, Jin, Bei, Jin, Yanli, Liu, Yizhi, Pan, Jingxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436505/
https://www.ncbi.nlm.nih.gov/pubmed/28529629
http://dx.doi.org/10.7150/thno.17451