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Overexpression of Insulin-Like Growth Factor 1 Enhanced the Osteogenic Capability of Aging Bone Marrow Mesenchymal Stem Cells

Many studies have indicated that loss of the osteoblastogenic potential in bone marrow mesenchymal stem cells (bmMSCs) is the major component in the etiology of the aging-related bone deficit. But how the bmMSCs lose osteogenic capability in aging is unclear. Using 2-dimentional cultures, we examine...

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Detalles Bibliográficos
Autores principales:	Chen, Ching-Yun, Tseng, Kuo-Yun, Lai, Yen-Liang, Chen, Yo-Shen, Lin, Feng-Huei, Lin, Shankung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436515/ https://www.ncbi.nlm.nih.gov/pubmed/28529639 http://dx.doi.org/10.7150/thno.16637

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