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Serotonergic activation during courtship and aggression in the brown anole, Anolis sagrei

The role of serotonin (5-hydroxytryptamine, 5-HT) in social behavior regulation is not fully understood. While 5-HT release in nuclei of the social behavior network has generally been associated with inhibition of aggressive behavior across multiple classes of vertebrates, less is known about its ef...

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Autores principales: Hartline, Jacob T., Smith, Alexandra N., Kabelik, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436558/
https://www.ncbi.nlm.nih.gov/pubmed/28533977
http://dx.doi.org/10.7717/peerj.3331
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author Hartline, Jacob T.
Smith, Alexandra N.
Kabelik, David
author_facet Hartline, Jacob T.
Smith, Alexandra N.
Kabelik, David
author_sort Hartline, Jacob T.
collection PubMed
description The role of serotonin (5-hydroxytryptamine, 5-HT) in social behavior regulation is not fully understood. While 5-HT release in nuclei of the social behavior network has generally been associated with inhibition of aggressive behavior across multiple classes of vertebrates, less is known about its effects on sexual, especially non-copulatory courtship display behaviors. Furthermore, most research has examined effects at 5-HT release sites, while studies examining the behavioral relevance of source cell populations have generated contradictory findings. This study utilized immunohistochemistry to examine the colocalization of 5-HT with Fos, an immediate early gene product and marker of neural activity, in the raphe and superior reticular nuclei of male brown anoles (Anolis sagrei) exposed to either aggression, courtship, or control social interactions. Supporting previous research, copulation was associated with a decrease in 5-HT activity, while a novel link between 5-HT activity and latency to non-copulatory courtship was also found. Within the aggression group, intensity and frequency of behavior were both associated with decreased 5-HT activity. An effect of social context was also seen, with anoles exposed to either courtship or aggression encounters showing decreased 5-HT activity in certain raphe and superior reticular nuclei populations compared to controls. Interestingly, context effects and behavioral effects were seen at separate brain nuclei, suggesting the presence of separate systems with distinct functional roles.
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spelling pubmed-54365582017-05-22 Serotonergic activation during courtship and aggression in the brown anole, Anolis sagrei Hartline, Jacob T. Smith, Alexandra N. Kabelik, David PeerJ Animal Behavior The role of serotonin (5-hydroxytryptamine, 5-HT) in social behavior regulation is not fully understood. While 5-HT release in nuclei of the social behavior network has generally been associated with inhibition of aggressive behavior across multiple classes of vertebrates, less is known about its effects on sexual, especially non-copulatory courtship display behaviors. Furthermore, most research has examined effects at 5-HT release sites, while studies examining the behavioral relevance of source cell populations have generated contradictory findings. This study utilized immunohistochemistry to examine the colocalization of 5-HT with Fos, an immediate early gene product and marker of neural activity, in the raphe and superior reticular nuclei of male brown anoles (Anolis sagrei) exposed to either aggression, courtship, or control social interactions. Supporting previous research, copulation was associated with a decrease in 5-HT activity, while a novel link between 5-HT activity and latency to non-copulatory courtship was also found. Within the aggression group, intensity and frequency of behavior were both associated with decreased 5-HT activity. An effect of social context was also seen, with anoles exposed to either courtship or aggression encounters showing decreased 5-HT activity in certain raphe and superior reticular nuclei populations compared to controls. Interestingly, context effects and behavioral effects were seen at separate brain nuclei, suggesting the presence of separate systems with distinct functional roles. PeerJ Inc. 2017-05-16 /pmc/articles/PMC5436558/ /pubmed/28533977 http://dx.doi.org/10.7717/peerj.3331 Text en ©2017 Hartline et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Animal Behavior
Hartline, Jacob T.
Smith, Alexandra N.
Kabelik, David
Serotonergic activation during courtship and aggression in the brown anole, Anolis sagrei
title Serotonergic activation during courtship and aggression in the brown anole, Anolis sagrei
title_full Serotonergic activation during courtship and aggression in the brown anole, Anolis sagrei
title_fullStr Serotonergic activation during courtship and aggression in the brown anole, Anolis sagrei
title_full_unstemmed Serotonergic activation during courtship and aggression in the brown anole, Anolis sagrei
title_short Serotonergic activation during courtship and aggression in the brown anole, Anolis sagrei
title_sort serotonergic activation during courtship and aggression in the brown anole, anolis sagrei
topic Animal Behavior
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436558/
https://www.ncbi.nlm.nih.gov/pubmed/28533977
http://dx.doi.org/10.7717/peerj.3331
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