Estradiol Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory T(H)2 Shift by Activating SGK1

A pro-inflammatory cytokine profile at the feto-maternal interface may predispose immune maladaptation notably in early miscarriages. We investigated the involvement of estradiol (E(2))-activated serum-glucocorticoid regulated kinase 1 (SGK1) in preserving the tolerogenic and pro-survival intrauteri...

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Detalles Bibliográficos
Autores principales: Lou, Yiyun, Hu, Minhao, Wang, Qijing, Yuan, Mu, Wang, Ning, Le, Fang, Li, Lejun, Huang, Shisi, Wang, Liya, Xu, Xiangrong, Jin, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436564/
https://www.ncbi.nlm.nih.gov/pubmed/28529452
http://dx.doi.org/10.7150/ijbs.18278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436564/
https://www.ncbi.nlm.nih.gov/pubmed/28529452
http://dx.doi.org/10.7150/ijbs.18278

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